Nucleosides and Analogues
Medchemexpress LLC UDP-Galactose disodi 100mg | 137868-52-1 | 100 MG
Udp-galactose disodium is a nucleotide sugar used as a donor substrate for galactosyltransferases and an endogenous agonist of the P2Y14 receptor. It is commonly used in glycobiology and enzymology research.
- Serves as a donor substrate for beta-1,4-galactosyltransferases.
- Acts as a P2Y14 receptor agonist (hP2Y14 EC50 ~0.67 μM).
- High purity suitable for biochemical assays.
- Available in multiple sizes, including 100 mg.
- Stable when stored sealed at 4°C; in solution, store at -80°C for long-term storage.
eMolecules 142439-94-9 | Medchem Express | Rp-cAMPS (sodium salt) | 1mg | 632433127 | HY-100530D | 367.25 | C10H11N5NaO5PS
Ambeed | 1-(2-Chloroethyl)-1H-imidazole hydrochloride | 1g | 490518319 | A160979 | 18994-78-0 | MFCD00799332 | 167.030 | C5H8Cl2N2
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Medchemexpress LLC N6,N6-dimethyladenosine | 2620-62-4 | MFCD00022822 | 100.0% | 295.29 g·mol⁻1 | C12H17N5O4 | 1 ML
N6,N6-dimethyladenosine is a modified ribonucleoside used as an analytical standard and research reagent. It is supplied as solid material or as a 10 mM solution in DMSO and is used in studies of RNA modification, cellular signaling (including AKT pathway modulation), and viral entry protein interactions.
- High purity (>99.9%) suitable for analytical use.
- Available as solid and 10 mM solution in DMSO for convenient handling.
- Molecular formula C12H17N5O4 and molecular weight 295.29 g·mol⁻1.
- Suitable for studies of RNA modification and cellular signaling.
- Certificate of analysis and safety data sheet available.
Medchemexpress LLC Adenosine A1 receptor activator T62 | 40312-34-3 | MFCD02738687 | 98.9% | 291.80 | C15H14ClNOS | 1 MG
Adenosine A1 receptor activator T62 is an allosteric enhancer of the adenosine A1 receptor used in preclinical research to study A1-mediated signaling and pain modulation. It produces antinociception in animal models of acute, inflammatory, and neuropathic pain.
- Allosteric enhancer of the adenosine A1 receptor.
- Demonstrated antinociception in animal models of acute, inflammatory, and neuropathic pain.
- High purity (~98.9%) suitable for research applications.
- Solid, light yellow to yellow, suitable for solid or solution preparations.
- Molecular formula C15H14ClNOS; molecular weight 291.80.
- Available in small-scale solid amounts and DMSO solution for in vitro use.
Medchemexpress LLC Uridine 5'-monophosphate | 58-97-9 | MFCD00067346 | 100.0% | 324.18 | C9H13N2O9P | 25 MG
Uridine 5'-monophosphate is a ribonucleotide provided as a high-purity reference standard intended for research and analytical applications. It is suitable for use in biochemical assays, analytical method development, and as a calibration standard.
- High purity 99.98%
- Molecular formula C9H13N2O9P
- Molecular weight 324.18 g/mol
- CAS number 58-97-9
- Pack size 25 mg
- Suitable as a reference standard for biochemical assays and analytical method development
Medchemexpress LLC Adenosine-13C10,15N5 | 202406-75-5 | MFCD28458760 | >98% | 25 MG
Adenosine-13C10,15N5 is a labeled adenosine, an endogenous purine nucleoside that acts as an important homeostatic regulator of physiological function and an anti-arrhythmic agent.
- Labeled adenosine
- Endogenous purine nucleoside
- Acts as an important homeostatic regulator of physiological function
- Functions as an anti-arrhythmic agent
- Modulates various physiological processes
- Activates G protein-coupled receptors (GPCRs), including adenosine receptors (ARs)
- Involved in energy metabolism
- Used in research for various diseases
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | >99.9% | 267.25 | 5 G
2'-Deoxyguanosine is a purine nucleoside with diverse biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively. This product is intended for research use only.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Intended for research applications.
Medchemexpress LLC Uridine 5'-monophosphate disodium salt | 3387-36-8 | 98.0% | 368.14 | 1 G
Uridine 5'-monophosphate disodium salt (Standard) is an analytical standard intended for research and analytical applications. It acts as an orally active mitochondrial ATP-dependent potassium channel activator, offering protective effects on the heart. This compound promotes CDP-choline synthesis and induces apoptosis in intestinal epithelial cells, supporting gut development and reducing diarrhea.
- Analytical standard for research and analytical applications
- Acts as an orally active mitochondrial ATP-dependent potassium channel activator
- Offers protective effects on the heart
- Promotes synthesis of CDP-choline
- Induces apoptosis in intestinal epithelial cells
- Beneficial for gut development
- Reduces diarrhea
- Used as a reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Cambridge Isotope Laboratories Adenosine 5-monophosphate ammonium salt (U-13C10 99% U-15N5 98%) CP 95% (in solution) 50 mg
Adenosine 5-monophosphate ammonium salt (U-13C10 99% U-15N5 98%) CP 95% (in solution) 50 mg
Selleck Chemical LLC Guanosine S2439-1g
Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a -N9-glycosidic bond
Chem-Impex International, Inc. 5-Iodo-2'-deoxyuridine | 54-42-2 | MFCD00134656 | 5G
5-Iodo-2'-deoxyuridine, 54-42-2, MFCD00134656, 5G
Medchemexpress LLC N6-Isopentenyladenosine | 7724-76-7 | 99.4% | 335.36 | 1 ML
N6-Isopentenyladenosine (Riboprine) is an RNA modification found in cytokinins, which are known to regulate plant growth and differentiation. It is also present in a subset of tRNAs, where it enhances the efficiency and accuracy of translation. This compound is an end product of the mevalonate pathway and functions as an autophagy inhibitor, demonstrating interesting anti-melanoma activity.
- RNA modification found in cytokinins
- Regulates plant growth/differentiation
- Improves efficiency and accuracy of translation in tRNAs
- End product of the mevalonate pathway
- Autophagy inhibitor
- Exhibits anti-melanoma activity